One in five bowel cancer 'red flag' symptoms missed


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One in five bowel cancer patients diagnosed in an emergency had “red flag” symptoms that should have been picked up earlier, a study in the British Journal of Cancer suggests.

And 16% of emergency bowel cancer patients had seen their GP three times or more with relevant symptoms.

But overall these symptoms were less common in patients diagnosed at an emergency stage rather than earlier on.

The study looked at data on diagnoses in England from 2005 to 2006.

The researchers, from University College London and the London School of Hygiene and Tropical Medicine, focused on what had happened to patients in the five years leading up to their cancer diagnosis.

They analysed National Cancer Registry data that was linked to GP data for 1,606 patients from more than 200 GP practices.


They found that in England 22% of bowel cancers – colon and rectal cancer – were diagnosed after an emergency presentation.

Although many of these patients often did not display obvious symptoms for bowel cancer, making it harder for GPs to diagnose their cancer early, 17.5% of colon cancer patients and 23% of rectal cancer patients did have “red flag” symptoms.

The researchers say this indicates there could have been opportunities to pick up the disease earlier.

Most patients, regardless of how they were diagnosed, visited their doctor in the year before their diagnosis.

And patients tended to see their doctors more often in the months and days leading up to their cancer diagnosis – whether it happened in an emergency or not.

The research team suggested that specially trained nurses could support GPs and act as a safety net during consultations.

Easier access to specialist advice for GPs was also important, the study said.

Most common symptoms during year before diagnosis among colon cancer patients:

  • abdominal pain
  • anaemia
  • diarrhoea
  • rectal bleeding

Among rectal cancer patients:

  • rectal bleeding
  • change in bowel habits
  • diarrhoea
  • abdominal pain

Cristina Renzi, lead researcher from University College London, said patients diagnosed with cancer after an emergency presentation did not fare as well as patients diagnosed by their GP.

“However, in most cases they visit their doctor for various reasons multiple times during the months leading up to their diagnosis, which could represent opportunities to diagnose the cancer earlier.

She added: “It’s important to find ways to ensure these patients can be diagnosed at an early stage.

“And this study highlights the need to support GPs and give them the tools to diagnose and refer patients promptly when they feel it’s necessary.”

Dr Julie Sharp, head of patient information and health at Cancer Research UK, said diagnosing patients who were not showing typical symptoms of bowel cancer was very difficult.

“So research like this, to understand more about people’s symptom histories, is crucial to find better ways to diagnose the disease at an early stage, when treatment is more likely to be successful.”


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